PromarkerESO

The Oesophageal Health Test is a blood test designed to rule out oesophageal cancer.
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Supporting risk assessment in patients with chronic reflux symptoms

The Oesophageal Cancer Risk Test is a blood-based assessment designed to support evaluation of oesophageal adenocarcinoma risk in appropriate patients presenting with chronic reflux symptoms and recognised risk factors.

Clinical Need

Chronic gastro-oesophageal reflux disease (GORD) is a recognised risk factor for oesophageal adenocarcinoma.

Many patients are diagnosed at later stages of disease, while current assessment pathways frequently rely on invasive investigation through endoscopy.

There is an increasing need for non-invasive approaches to assist risk assessment and support referral decisions.

Patient Eligibility

Suitable for adults who:

  • Have experienced chronic heartburn or acid reflux for five years or longer
  • Are over 50 years of age
  • Have a BMI greater than 25 kg/m²
  • Have at least two recognised risk factors for oesophageal adenocarcinoma
  • Have not previously been diagnosed with cancer

How the test works

The test analyses four protein biomarkers associated with oesophageal adenocarcinoma and combines these with clinical variables including age, sex and BMI to generate a personalised risk score.

Results are reported as:

  • Low Probability
  • Moderate Probability
  • High Probability

With guidance regarding further investigation pathways.

Role alongside current assessment

The Oesophageal Cancer Risk Test may assist clinicians by:

  • Supporting assessment of oesophageal adenocarcinoma risk
  • Providing a non-invasive blood-based assessment
  • Supporting patient discussions regarding reflux-associated cancer risk
  • Informing decisions regarding further investigation or specialist referral
  • Complementing standard clinical evaluation and existing diagnostic pathways

How to request and access the test

PromarkerESO can be requested by using a standard pathology request form. The test is exclusively available through pathology network and is performed on a routine blood sample.

Results help identify patients whose risk profile may warrant further investigation or specialist referral, alongside clinical assessment and existing management pathways.

Price and Medicare status

PromarkerESO is currently a privately funded test and is not covered by Medicare.

Please refer to current pricing information for patient out-of-pocket costs and payment arrangements.

Sample collection requirements

PromarkerESO requires a routine blood sample collected at a participating Laverty Pathology collection centre.

No specialised collection procedure is required. Specimens are transported to the testing laboratory under validated conditions for analysis.

Resources

FAQ

Who is eligible for this test?
Does this test diagnose oesophageal adenocarcinoma?
Does this replace endoscopy?
What information is used to calculate the risk score?
How is the sample collected?